Welcome to the Frazer Lab! We've been applying two complementary approaches to realize our intention of figuring out and characterizing useful human genetic variants. Our very first technique makes use of iPSCORE, a source that was created to enable equally familial and association-dependent genetic reports of molecular and physiological phenotypes

cAMP-dependent protein kinase (PKA) is ubiquitous in just about every mammalian cell While using the PKA signaling network regulating procedures as assorted as memory, differentiation, growth, the mobile cycle, and circadian rhythms. One among our plans, in addition to elucidating structures of your PKA subunits, will be to map the PKA proteome as

Assessment of these mutants will allow elucidation from the genetic networks that avoid genome instability in addition to those who purpose during the DNA harm response. Versions on this project incorporate executing a world mutant Assessment, investigating specific pathways for instance double strand crack fix and their interacting pathways, and b

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We even have labels to help you have additional Command by the procedure. The this means of every of those labels is: It performs interpretation and Investigation of the assorted Organic data like amino acid sequences, nucleotide sequences, and so on.Within the not as well distant future with using bioinformatics tool, the potential for employin